Buy cheap Tofranil

Tofranil (Imipramine) is an antidepressant medication, a tricyclic antidepressant of the dibenzazepine group. Tofranil (Imipramine) is mainly used in the treatment of clinical depression and enuresis.

Tofranil (Imipramine), a tertiary amine, inhibits the reuptake of serotonin more than most secondary amine tricyclics, as it blocks the reuptake of the neurotransmitters serotonin and norepinephrine almost equally (a little more norepinephrine anyway). Imiparmine also has activity at delta opiate receptors as well as substantial activity at D1 and D2 dopamine receptors [1] Enhancement of brain dopamine activity has been implicated in Tofranil (Imipramine)'s ability to stimulate motor activity and prolong time spent in escape in mice, and opiate activity is thought to contribute to it analgesic effect. It is an antagonist at histamine H1 and alpha-1-adrenoceptors. In addition, the drug is an antagonist at M2 muscarinic acetylcholine receptors (see external links).

After taking the medicine Tofranil (Imipramine) may cause some side effects in some patients, particularly with the first few doses.

Allergic effects:

Isolated cases of pneumonitis (fever, chills, cough, difficulty with breathing, unusual weight loss, feeling sick) have been reported. A puffy, swollen face, tongue or body has been reported. These reactions may be severe, causing shortness of breath, swelling, shock and collapse. If you develop any allergic symptoms, stop taking the medicine and contact your doctor immediately.

Effects on the blood:

Isolated changes in blood cells. If you notice that you are bruising more frequently or have more nosebleeds or infections you should consult your doctor.

Effects on the heart:

Arrhythmias: Irregular heart rhythms.

Effects on the endocrine system and metabolism:

Weight gain has been reported frequently. Disturbances in sexual function have been reported occasionally. Isolated cases of enlarged mammary glands, production or over-production of breast milk, increased or decreased blood sugar levels and weight loss have been reported. Low levels of salt in the blood have been reported, usually in elderly patients, which can be identified by a blood test.

Effects on the brain and central nervous system:

Tremor has been reported frequently. Headache, confusion, orthostatic hypotension (resulting in dizziness upon standing), numbness/tingling, agitation, anxiety, restlessness, mood swings, exaggerated behaviour, delusions and hallucinations have been reported occasionally and are more common in the elderly or in patients on high doses. Aggressiveness, weakness, lack of co-ordination, sudden muscle spasms, difficulty speaking have been reported in isolated cases.

Tofranil (Imipramine) also enhances the CNS effects of both stimulants and alcohol, and blocks the parasympathomimetic effects of stimulants while enhancing the cortical excitation. This can be dangerous in some cases and result in seizures and coma.

Effects on the ears:

Ringing or buzzing in the ears have been reported.

Effects on the stomach and intestines:

Feeling or being sick and loss of appetite have been reported occasionally. Isolated cases of tongue lesions and inflammation of the mucus membranes in the mouth have been reported.

Effects on the liver:

Changes in liver function have been reported occasionally. This would be identified by a blood test. Hepatitis and jaundice (yellowing of the skin and/or whites of the eyes) have been reported in isolated cases.

Effects on the skin:

Allergic reactions such as an itchy skin rash have been reported occasionally. Isolated cases of swelling, sensitivity to the sun or sun lamps, hair loss, small purple red spots and itching have been reported.

Withdrawal:

If the medicine is stopped too quickly, there is the possibility the user may suffer from feeling or being sick, stomach pains, diarrhea, headache, sleeplessness, nervousness, anxiety, irritability and increased sweating.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.